Article

Nutrient restriction, inducer of yeast meiosis, induces mammalian meiotic initiation

2020-07-14

Abstract excerpt

From yeasts to mammals, the molecular machinery and chromosome structures carrying out meiosis are frequently conserved. However, the signal to initiate meiosis appears divergent: while nutrient restriction induces meiosis in the yeast system, retinoic acid (RA), a chordate morphogen, and its target, Stra8, are necessary but not sufficient to induce meiotic initiation in mammalian germ cells. Here, by using a comb...

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Literature Corpus work: 10846939-2b9c-58da-b84a-16fac5312b7b
DOI: 10.21203/rs.3.rs-35893/v1

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