Article

Integrating Predicted Transcriptome From Multiple Tissues Improves Association Detection

2018-03-31

Abstract excerpt

Integration of genome-wide association studies (GWAS) and expression quantitative trait loci (eQTL) studies is needed to improve our understanding of the biological mechanisms underlying GWAS hits, and our ability to identify therapeutic targets. Gene-level association test methods such as PrediXcan can prioritize candidate targets. However, limited eQTL sample sizes and absence of relevant developmental and disea...

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Literature Corpus work: ec91b4db-9fac-53b4-afb9-278420fff59b
DOI: 10.1101/292649

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