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Transcriptomic Analysis of Cellular Senescence: One Step Closer to Senescence Atlas

1 Mar 2021

Abstract excerpt

Senescent cells that gradually accumulate during aging are one of the leading causes of aging. While senolytics can improve aging in humans as well as mice by specifically eliminating senescent cells, the effect of the senolytics varies in different cell types, suggesting variations in senescence. Various factors can induce cellular senescence, and the rate of accumulation of senescent cells differ depending on...

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PMID: 33795532
DOI: 10.14348/molcells.2021.2239

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