Article
Senescent cells at the crossroads of aging, disease, and tissue homeostasis
20 Sept 2023
Abstract excerpt
Originally identified as an outcome of continuous culture of primary cells, cellular senescence has moved beyond the culture dish and is now a bona fide driver of aging and disease in animal models, and growing links to human disease. This cellular stress response consists of a stable proliferative arrest coupled to multiple phenotypic changes. Perhaps the most important of these is the senescence-associated...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.