Article

NIH SenNet Consortium: Mapping Senescent Cells in the Human Body to Understand Health and Disease

2022-09-15

Abstract excerpt

Cells respond to a myriad of stressors by senescing, acquiring stable growth arrest, morphologic and metabolic changes, and a senescence-associated-secretory-phenotype (SASP). The heterogeneity of senescent cells (SnCs) and their SASP is vast, yet poorly characterized. SnCs have diverse roles in health and disease and are therapeutically targetable, making characterization of SnCs and harmonization of their nomenc...

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Literature Corpus work: 4ee83cec-741f-57dc-89d3-fddd3b384f17
DOI: 10.20944/preprints202207.0160.v2

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