Article

Zfp503/Nlz2 is Required for RPE Differentiation and Optic Fissure Closure

2022-03-29

Abstract excerpt

<h4>Purpose</h4> Uveal coloboma is a congenital eye malformation caused by failure of the optic fissure to close in early human development. Despite significant progress in identifying genes whose regulation is important for executing this closure, mutations are detected in a minority of cases using known gene panels, implying additional genetic complexity. We have previously shown knock down of znf503 (the orth...

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Literature Corpus work: ec31072b-cb81-56ef-a75f-6b91fd418849
DOI: 10.1101/2022.03.28.486078

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