Article

Mitf-family transcription factor function is required within cranial neural crest cells to promote choroid fissure closure

2019-12-08

Abstract excerpt

A critical step in eye development is closure of the choroid fissure (CF), a transient structure in the ventral optic cup through which vasculature enters the eye and ganglion cell axons exit. While many factors have been identified that function during CF closure, the molecular and cellular mechanisms mediating this process remain poorly understood. Failure of CF closure results in colobomas. Recently, MITF was...

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Literature Corpus work: 04c5882c-f3fc-5796-9906-537c75f985c5
DOI: 10.1101/869040

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