Article

Genetic Variation in the Oestrogen Pathway and Cancer-Associated Cachexia: Implications for Disease Predictive and Supportive Care

2026-05-28

Abstract excerpt

<title>Abstract</title> <p> Purpose Cancer-associated cachexia (CAC) affects over 50% of cancer patients and accounts for approximately 20% of cancer-related deaths, highlighting the need for reliable tools to predict its onset and aid in supportive care. Accumulating evidence suggests that CAC pathogenesis has a strong hormonal component and is also influenced by inherited genetic factors. This study investiga...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: ec000b16-fbb3-57f1-a9e3-cbd93570afa9
DOI: 10.21203/rs.3.rs-9305705/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Genetic Variation in the Oestrogen Pathway and Cancer-Associated Cachexia: Implications for Disease Predictive and Supportive CareDOI 10.21203/rs.3.rs-9305705/v1Read

Vitamin D Receptor rs731236 Polymorphism Modulates Cancer Cachexia Susceptibility and Overall Survival: A Real-World Study on Context- Dependent Vitamin D SignallingSemantic proximity Read

Genetic Variability in the IGF-1 Axis Modulates Cancer-Associated Cachexia and PrognosisSemantic proximity Read

Genetic basis of interindividual susceptibility to cancer cachexia: selection of potential candidate gene polymorphisms for association studies.Semantic proximity Read

Vitamin D Receptor rs731236 Polymorphism Modulates Cancer Cachexia Susceptibility and Overall Survival: A Real-World Study on Context-Dependent Vitamin D Signalling.Semantic proximity Read

Identification of possible genetic polymorphisms involved in cancer cachexia: a systematic review.Semantic proximity Read

Biomarkers for cancer cachexia: is there also a genetic component to cachexia?Semantic proximity Read

Variants of estrogen-related genes and breast cancer risk in European and African American women.Semantic proximity Read

Unique ESR1 and ESR2 estrogen receptor gene variants associated with altered risk of triple-negative breast cancer: A case-control study.Semantic proximity Read

Impact of COX2 genotype, ER status and body constitution on risk of early events in different treatment groups of breast cancer patients.Semantic proximity Read

A common polymorphism near the ESR1 gene is associated with risk of breast cancer: evidence from a case-control study and a meta-analysis.Semantic proximity Read

Estrogen receptor 1 (ESR1) genetic variations in cancer risk: a systematic review and meta-analysis.Semantic proximity Read

Energy homeostasis genes and breast cancer risk: The influence of ancestry, body size, and menopausal status, the breast cancer health disparities study.Semantic proximity Read