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Vitamin D Receptor rs731236 Polymorphism Modulates Cancer Cachexia Susceptibility and Overall Survival: A Real-World Study on Context- Dependent Vitamin D Signalling

2026-05-12

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<title>Abstract</title> <p> Purpose Cancer-associated cachexia (CAC) is a complex metabolic syndrome characterised by progressive skeletal muscle loss, systemic inflammation, reduced treatment tolerance, and poor survival. Individual susceptibility to CAC varies considerably, suggesting a contribution of host genetic factors. Vitamin D plays an important role in muscle metabolism and inflammatory control throug...

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Literature Corpus work: 34b4080b-0baa-5f0f-8ff9-432f87401908
DOI: 10.21203/rs.3.rs-9670248/v1

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