Article
Identification of possible genetic polymorphisms involved in cancer cachexia: a systematic review.
Journal of genetics - 1 Apr 2011
Tan Benjamin H L, Ross James A, Kaasa Stein, Skorpen Frank, Fearon Kenneth C H
Abstract excerpt
Cancer cachexia is a polygenic and complex syndrome. Genetic variations in regulation of the inflammatory response, muscle and fat metabolic pathways, and pathways in appetite regulation are likely to contribute to the susceptibility or resistance to developing cancer cachexia. A systematic search of Medline and EmBase databases, covering 1986-2008 was performed for potential candidate genes/genetic polymorphisms...
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