Article

<i>Brucella</i> suppress innate immunity by down-regulating STING expression in macrophages

2020-01-02

Abstract excerpt

Brucellosis, caused by Brucella bacteria species, remains the most prevalent zoonotic disease worldwide. Brucella establish chronic infections within host macrophages despite triggering cytosolic innate immune sensors, including Stimulator of Interferon Genes (STING), which potentially limit infection. In this study, STING was required for control of chronic Brucella infection in vivo . However, early during i...

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Literature Corpus work: ebc4fa28-b6e5-56fb-984e-2136b49fab69
DOI: 10.1101/2019.12.31.891051

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