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The opportunistic intracellular bacterial pathogen <i>Rhodococcus equi</i> elicits type I interferons by engaging cytosolic DNA sensing in macrophages

2021-03-29

Abstract excerpt

<h4>ABSTRACT</h4> Rhodococcus equi is a major cause of foal pneumonia and an opportunistic pathogen in immunocompromised humans. While alveolar macrophages constitute the primary replicative niche for R. equi , little is known about how intracellular R. equi is sensed by macrophages. Here, we discovered that that in addition to previously characterized pro-inflammatory cytokines (e.g., Tnfa, Il6, Il1b), macroph...

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Literature Corpus work
c9d0d40c-7f23-540f-969f-027a0b914e14
DOI
10.1101/2021.03.28.437424
Open publication

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The opportunistic intracellular bacterial pathogen <i>Rhodococcus equi</i> elicits type I interferons by engaging cytosolic DNA sensing in macrophagesDOI 10.1101/2021.03.28.437424
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