Article

Cross-talk between intracellular pathogen infection and IFNγ signaling drives enhanced pro-inflammatory responses

2026-05-27

Abstract excerpt

Many intracellular pathogens have evolved to evade immune responses and establish a secure niche inside host cells. One such stealth pathogen is the obligate intracellular bacterium Coxiella burnetii , the causative agent of Q-fever. Coxiella translocates an array of bacterial proteins (‘effectors’) into the host cell through a type IVB secretion system (T4BSS) that mediates suppression of pathogen sensing and i...

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Literature Corpus work: 308221ac-a759-5a8d-8c1e-5c071091bd5c
DOI: 10.64898/2026.05.23.726403

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