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Article

Genetic requirements of <i>Mycobacterium tuberculosis</i> for survival under pathogen-specific immunity

2024-09-29

Abstract excerpt

<h4>ABSTRACT</h4> Mycobacterium tuberculosis (Mtb), the etiologic agent of tuberculosis (TB), remains a persistent global health challenge due to the lack of an effective vaccine. The only licensed TB vaccine, Bacille Calmette-Guerin (BCG), is a live attenuated strain of Mycobacterium bovis , that protects young children from severe disease but fails to provide protection through adulthood. It is unclear why BCG...

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Literature Corpus work
eba329cd-96f7-59b9-8eff-27c20502f499
DOI
10.1101/2024.09.26.615000
Open publication

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Genetic requirements of <i>Mycobacterium tuberculosis</i> for survival under pathogen-specific immunityDOI 10.1101/2024.09.26.615000
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