Article

An unexpected contribution of lincRNA splicing to enhancer function

2018-03-23

Abstract excerpt

<h4>ABSTRACT</h4> Transcription is common at active mammalian enhancers sometimes giving rise to stable and unidirectionally transcribed enhancer-associated long intergenic noncoding RNAs (elincRNAs). ElincRNA expression is associated with changes in neighboring gene product abundance and local chromosomal topology, suggesting that transcription at these loci contributes to gene expression regulation in cis . De...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: eb8562bb-e621-59d7-8132-5184bda3eef4
DOI: 10.1101/287706

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

An unexpected contribution of lincRNA splicing to enhancer functionDOI 10.1101/287706Read

The activity of human enhancers is modulated by the splicing of their associated lncRNAsSemantic proximity Read

Chromatin environment, transcriptional regulation, and splicing distinguish lincRNAs and mRNAsSemantic proximity Read

Functional anatomy of distant-acting mammalian enhancers.Semantic proximity Read

An atlas of active enhancers across human cell types and tissues.Semantic proximity Read

Mammalian enhancers and GWASs act proximally and seldom skip active genesSemantic proximity Read

Genomic Language Model for Predicting Enhancers and Their Allele-Specific Activity in the Human GenomeSemantic proximity Read

A High-Resolution Map of Human Enhancer RNA Loci Characterizes Super-enhancer Activities in Cancer.Semantic proximity Read

Comprehensive characterization genetic regulation and chromatin landscape of enhancer-associated long non-coding RNAs and their implication in human cancer.Semantic proximity Read

Genome-wide Enhancer Maps Differ Significantly in Genomic Distribution, Evolution, and FunctionSemantic proximity Read

Dynamics and Topology of Human Transcribed <i>Cis</i> -regulatory ElementsSemantic proximity Read

Enhancer biology and enhanceropathies.Semantic proximity Read

eRNA-IDO: a one-stop platform for identification, interactome discovery and functional annotation of enhancer RNAsSemantic proximity Read