Article

Systematic Evaluation of Cell Type Deconvolution Methods for Plasma Cell-free DNA

2024-03-29

Abstract excerpt

Plasma cell-free DNA (cfDNA) is derived from cellular death in various tissues. Investigating the origin of cfDNA through tissue/cell type deconvolution allows us to detect changes in tissue homeostasis that occur during disease progression or in response to treatment. Consequently, cfDNA has emerged as a valuable noninvasive biomarker for disease detection and treatment monitoring. Although there are numerous met...

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Literature Corpus work: eb4565f1-2aa6-582f-83ac-f4bab2e64ada
DOI: 10.1101/2024.03.25.586507

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