Article

Benchmarking of Methods for DNA Methylome Deconvolution

2023-10-31

Abstract excerpt

<title>Abstract</title> <p>Defining the number and abundance of different cell types in tissues is important for understanding disease mechanisms as well as for diagnostic and prognostic purposes. Typically, this is achieved by immunohistological analyses, cell sorting, or single-cell RNA-sequencing. Alternatively, cell-specific DNA methylome information can be leveraged to deconvolute cell fractions from a bulk...

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Literature Corpus work: b64a66d4-c47e-5075-92b3-bc2db9753b78
DOI: 10.21203/rs.3.rs-3470543/v1

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