Article

Inducible transgene expression in CHO cells using an artificial transcriptional activator with estrogen-binding domain

2023-07-26

Abstract excerpt

Biopharmaceuticals, including therapeutic antibodies, are rapidly growing products in the pharmaceutical market. Mammalian cells, such as Chinese hamster ovary (CHO) cells, are widely used as production hosts because recombinant antibodies require complex three-dimensional structures modified with sugar chains. Recombinant protein production using mammalian cells is generally performed in conjunction with cell gro...

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Literature Corpus work: eb0e098c-bbc4-5610-b455-fce3ee572d1d
DOI: 10.22541/au.169036984.40514077/v1

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