Article

Targeting the RHOA pathway improves learning and memory in adult Kctd13 and 16p11.2 deletion mouse models

2020-11-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Gene copy number variants play an important role in the occurrence of neurodevelopmental disorders. Particularly, the deletion of the 16p11.2 locus is associated with autism spectrum disorder, intellectual disability, and several other features. Earlier studies highlighted the implication of <italic>Kctd13 </italic>genetic imbalance in 16p11.2 deletion through t...

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Literature Corpus work: eab8009a-86be-5e51-b43a-9dc456200e1f
DOI: 10.21203/rs.3.rs-60136/v2

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