Article

CHI3L1 (YKL-40) and Chit-1 expressing glia in the white matter of ALS, FTLD, and AD correlate to pathology and disease duration

2025-05-07

Abstract excerpt

<h4>Background: </h4> Chitotriosidase (Chit-1) and chitinase-3-like protein 1 (CHI3L1) protein levels are increased in the cerebrospinal fluid (CSF) of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS), frontotemporal dementia (FTD), and Alzheimers disease (AD). Few studies have examined the spatial expression of chitinase expressing cells with respect to neuropathologic hallmarks of diseas...

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Literature Corpus work: ea8fa4b8-2ec3-5ab8-a51d-5132f91fe6a2
DOI: 10.1101/2025.05.05.25326702

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CHI3L1 (YKL-40) and Chit-1 expressing glia in the white matter of ALS, FTLD, and AD correlate to pathology and disease durationDOI 10.1101/2025.05.05.25326702Read

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