Article

Chitinases in tear fluid of patients with Amyotrophic Lateral Sclerosis

2026-02-05

Abstract excerpt

<h4>Background</h4> Chitinases, including chitotriosidase (CHIT1) and chitinase-3-like protein 1 (CHI3L1), are markers of neuroinflammation, a key process in amyotrophic lateral sclerosis (ALS). Tear fluid (TF) can be collected non-invasively and may represent a promising alternative to CSF or blood to study chitinases. <h4>Methods</h4> TF was collected from 50 ALS patients and 50 control subjects using Schirmer...

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Literature Corpus work: 81701eec-1e91-58ff-8a59-61a10388a3c4
DOI: 10.64898/2026.02.04.26345568

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