Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Astrocytic Chitinase‐3‐like protein 1 in neurological diseases: Potential roles and future perspectives

7 Apr 2023

Abstract excerpt

Chitinase-3-like protein 1 (CHI3L1) is a secreted glycoprotein characterized by its ability to regulate multiple biological processes, such as the inflammatory response and gene transcriptional signaling activation. Abnormal CHI3L1 expression has been associated with multiple neurological disorders and serves as a biomarker for the early detection of several neurodegenerative diseases. Aberrant CHI3L1 expression...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Insect symbiosis and bacterial influences
Share to Mosquito-borne diseases and control
Share to Studies on Chitinases and Chitosanases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 37026513
DOI: 10.1111/jnc.15824

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Astrocytic Chitinase‐3‐like protein 1 in neurological diseases: Potential roles and future perspectivesPMID 37026513Read ↗

CHI3L1 drives astrocyte-medicated neuronal injury via GAL3-NLRP3 signaling in ischemic strokeSemantic proximity Read ↗

CHI3L1 predicted in malignant entities is associated with glioblastoma immune microenvironmentSemantic proximity Read ↗

Chitinase Signature in the Plasticity of Neurodegenerative DiseasesSemantic proximity Read ↗

Recently updated role of Chitinase 3-like 1 on various cell types as a major infuencer of chronic inflammationSemantic proximity Read ↗

In vivo CHI3L1 (YKL-40) expression in astrocytes in acute and chronic neurological diseasesSemantic proximity Read ↗

YKL-40/CHI3L1 drives inflammation on the road of tumor progressionSemantic proximity Read ↗

Targeting CHI3L1 in Alzheimer’s Disease: Optimization of G721-0282 and Functional Evaluation in Astrocyte ModelsSemantic proximity Read ↗

Chitinase-3-like Protein 1: A Progranulin Downstream Molecule and Potential Biomarker for Gaucher Disease.Semantic proximity Read ↗

K284-6111 Alleviates Memory Impairment and Neuroinflammation in Tg2576 Mice by Inhibition of Chitinase-3-like 1 Regulating ERK Dependent PTX3 PathwaySemantic proximity Read ↗

CHI3L1 (Chitinase 3 Like 1) upregulation is associated with macrophage signatures in esophageal cancerSemantic proximity Read ↗

Future Perspectives and Conclusions from Animal Models of CHI3L1-Related Inflammation-Associated CancerSemantic proximity Read ↗

CHI3L1 (YKL-40) and Chit-1 expressing glia in the white matter of ALS, FTLD, and AD correlate to pathology and disease durationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.