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Article

CSF biomarkers of neuroinflammation in distinct forms and subtypes of neurodegenerative dementia

31 Dec 2019

Abstract excerpt

BACKGROUND: In neurodegenerative dementias (NDs) such as prion disease, Alzheimer's disease (AD), and frontotemporal lobar degeneration (FTLD), protein misfolding leads to the tissue deposition of protein aggregates which, in turn, trigger neuroinflammation and neurodegeneration. Cerebrospinal fluid (CSF) biomarkers have the potential to reflect different aspects of these phenomena across distinct...

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PMID: 31892365
DOI: 10.1186/s13195-019-0562-4

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