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Bioengineer mesenchymal stem cell for Treatment of glioma by IL-12 mediated microenvironment reprogramming and nCD47-SLAMF7 mediated phagocytosis regulation of macrophages

2024-03-09

Abstract excerpt

High expression of cellular self-activated immunosuppressive molecules and extensive infiltration of suppressive immune cells in the tumor microenvironment are the main factors leading to the resistance of glioma to immunotherapy. However, the technology related to modifying the expression of glioma cellular self-molecules based on gene editing still needs to be developed. In this project, cell therapy strategies...

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Literature Corpus work
ea69c9d7-b93d-56ea-aee0-187119a27bdb
DOI
10.22541/au.170994437.77141754/v1
Open publication

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Bioengineer mesenchymal stem cell for Treatment of glioma by IL-12 mediated microenvironment reprogramming and nCD47-SLAMF7 mediated phagocytosis regulation of macrophagesDOI 10.22541/au.170994437.77141754/v1
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