Article

Self-adjuvant nanovaccine delivering cytokines as a novel platform to empower glioblastoma immunotherapy

2023-11-01

Abstract excerpt

Glioblastoma (GBM) is a highly aggressive and deadly malignant primary brain tumor with a median survival time of less than 15 months upon disease diagnosis. While immunotherapies have shown promising results in solid cancers, brain cancers are still unresponsive to immunotherapy due to immunological dysfunction and the presence of a blood-brain barrier. Interleukin (IL)-12 is one of the most potent cytokines used...

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Literature Corpus work: 80e30133-56ed-5d82-b9b6-7825b925c84d
DOI: 10.21203/rs.3.rs-3501528/v1

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