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Cancer Stem Cells and Immunosuppressive Microenvironment in Glioma

21 Dec 2018

Abstract excerpt

Glioma is one of the most common malignant tumors of the central nervous system and is characterized by extensive infiltrative growth, neovascularization, and resistance to various combined therapies. In addition to heterogenous populations of tumor cells, the glioma stem cells (GSCs) and other nontumor cells present in the glioma microenvironment serve as critical regulators of tumor progression and recurrence....

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PMID: 30619286
DOI: 10.3389/fimmu.2018.02924

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