Article

Quantifying the potential for future gene therapy to lower lifetime risk of polygenic late-onset diseases

2018-08-13

Abstract excerpt

<h4>ABSTRACT</h4> <h4>Background</h4> Within the next few decades, gene therapy techniques and genetic knowledge may sufficiently advance to support prophylactic gene therapy to prevent polygenic late-onset diseases. A combination of a large number of common low effect gene variants offers the most likely explanation for the heritability of the majority of these diseases, and their risk may be lowered by correct...

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Literature Corpus work: ea4eed2f-56f3-502a-9243-b134a2da03fa
DOI: 10.1101/390773

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