Article

Natural selection increases mutational robustness in complex diseases: Mendelian evidence from early versus late onset common diseases

2013-07-17

Abstract excerpt

<h4>Background: </h4> Natural selection operates on genetically influenced phenotypic variations that confer differential survival or reproductive advantages. Common diseases are frequently associated with increased mortality and disability and complex heritable factors play an important role in their pathogenesis. Hence, common diseases should trigger the process of natural selection with subsequent population ge...

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Literature Corpus work: bfd36003-9d88-5dcf-b241-ee47dbcbad6a
DOI: 10.7287/peerj.preprints.42v1

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