Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Dissection of the host-pathogen interaction in human tuberculosis using a bioengineered 3-dimensional model

7 Jan 2017

Abstract excerpt

Cell biology differs between traditional cell culture and 3-dimensional (3-D) systems, and is modulated by the extracellular matrix. Experimentation in 3-D presents challenges, especially with virulent pathogens. Mycobacterium tuberculosis (Mtb) kills more humans than any other infection and is characterised by a spatially organised immune response and extracellular matrix remodelling. We developed a 3-D system...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to 3D Printing in Biomedical Research
Share to Immune cells in cancer
Share to Tuberculosis Research and Epidemiology

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28063256
DOI: 10.7554/elife.21283

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Dissection of the host-pathogen interaction in human tuberculosis using a bioengineered 3-dimensional modelPMID 28063256Read ↗

3D Hydrogel Culture System Recapitulates Key Tuberculosis Phenotypes and Demonstrates Pyrazinamide Efficacy.Semantic proximity Read ↗

A bovine pulmosphere model and multiomics analyses identify a signature of early host response to <i>Mycobacterium tuberculosis</i> infectionSemantic proximity Read ↗

Lung-mimicking 3-Dimensional hydrogel culture system recapitulates key tuberculosis phenotypes and demonstrates pyrazinamide efficacySemantic proximity Read ↗

A bovine pulmosphere model and multiomics reveal early host response signature in tuberculosisSemantic proximity Read ↗

Generating Three-dimensional Human Granulomas in vitro to Study Mycobacterium tuberculosis-Host InteractionSemantic proximity Read ↗

Visualizing the dynamics of tuberculosis pathology using molecular imagingSemantic proximity Read ↗

Identification and characterization of host-directed therapeutics for tuberculosis using a versatile human 3D tuberculoma bioplatformSemantic proximity Read ↗

Host-directed therapies targeting the tuberculosis granuloma stromaSemantic proximity Read ↗

Methods for Evaluating the Effects of 2D and 3D Culture Environment on Macrophage Response to Mycobacterium InfectionSemantic proximity Read ↗

The Secret Lives of the Pathogenic MycobacteriaSemantic proximity Read ↗

Mycobacterium tuberculosisinfection of host cells in space and timeSemantic proximity Read ↗

Dual human lung models reveal compartment-specific activity of anti-tuberculosis drugs and host-directed therapiesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.