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Article

A Novel In Vitro Human Granuloma Model of Sarcoidosis and Latent Tuberculosis Infection

9 Jun 2017

Abstract excerpt

Many aspects of pathogenic granuloma formation are poorly understood, requiring new relevant laboratory models that represent the complexity (genetics and diversity) of human disease. To address this need, we developed an in vitro model of granuloma formation using human peripheral blood mononuclear cells (PBMCs) derived from patients with active sarcoidosis, latent tuberculosis (TB) infection (LTBI), or normal...

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PMID: 28598206
DOI: 10.1165/rcmb.2016-0321oc

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