Article

From tissue to subcellular level : imaging human precision-cut lung slices (PCLS) to gain insight into pandemic bacterial or viral infections

2024-09-05

Abstract excerpt

We describe a method for the generation and deep imaging of human precision-cut lung slices (PCLS). PCLS bridge the gap between in vivo and in vitro studies, providing a robust system for visualizing events from tissue to subcellular levels in the three-dimensional lung environment, with the preservation of all resident cell types and cell-cell interactions. They also constitute a validated model for studying ho...

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Literature Corpus work: bdafef26-37e7-59f4-b2a3-5b083351b715
DOI: 10.1101/2024.09.04.611185

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