Article

Ongoing Hurdles in Harnessing Xist to Treat Human Disease: Review Article

2025-02-11

Abstract excerpt

XIST RNA is one of the most important long non-coding RNAs and plays a significant role in X-chromosome inactivation during early mammalian development. This epigenetic process ensures dosage compensation between males (XY) and females (XX) by silencing one of the two X chromosomes in females. Beyond its classical function, XIST is emerging as a biomolecule of interest due to its involvement in diverse pathologica...

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Literature Corpus work: e97d34cc-537d-5512-bc11-2e21e5396229
DOI: 10.20944/preprints202502.0861.v1

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