Article

Enhanced Expression and Solubility of Main Protease (Mpro) of SARS-CoV-2 from E. Coli

2022-12-23

Abstract excerpt

The COVID-19 pandemic has posed disastrous consequences for the world. Main protease (Mpro) of SARS-CoV-2 is a safe and promising target mainly because it is conserved across variants and has no overlap with human proteases. Large quantities of Mpro are required for the screening of different inhibitors effective against SARS-CoV-2. In the present study, Mpro of SARS-CoV-2 was successfully cloned and expressed in...

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Literature Corpus work: e973d890-96a9-5647-929e-87f8f4bf5208
DOI: 10.2139/ssrn.4308588

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