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Structure-Based Virtual Screening to Discover Potential Lead Molecules for the SARS-CoV‑2 Main Protease

20 Jul 2020

Abstract excerpt

Abstract The COVID-19 disease is caused by a new strain of the coronavirus family (SARS-CoV-2), and it has affected at present millions of people all over the world. The indispensable role of the main protease (Mpro) in viral replication and gene expression makes this enzyme an attractive drug target. Therefore, inhibition of SARS-CoV-2 Mpro as a proposition to halt virus ingression is being pursued by scientists...

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PMID: 32687345
DOI: 10.1021/acs.jcim.0c00546

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