Article

Main protease mutants of SARS-CoV-2 variants remain susceptible to nirmatrelvir (PF-07321332)

2021-11-30

Abstract excerpt

The COVID-19 pandemic continues to be a public health threat. Multiple mutations in the spike protein of emerging variants of SARS-CoV-2 appear to impact on the effectiveness of available vaccines. Specific antiviral agents are keenly anticipated but their efficacy may also be compromised in emerging variants. One of the most attractive coronaviral drug targets is the main protease (M pro ). A promising M pro in...

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Literature Corpus work: 9e45dbd4-df55-5dd7-aa84-c84f33fad6ed
DOI: 10.1101/2021.11.28.470226

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