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<i>Burkholderia pseudomallei</i> BicA protein promotes pathogenicity in macrophages by regulating Invasion, Intracellular Survival, and Virulence

2023-07-10

Abstract excerpt

Burkholderia pseudomallei (Bpm) is the causative agent of melioidosis disease. Bpm is a facultative intracellular pathogen with a complex lifecycle inside host cells. Pathogenic success depends on a variety of virulence factors with one of the most critical being the type 6 secretion system (T6SS). Bpm uses the T6SS to move into neighboring cells, resulting in multinucleated giant cells (MNGCs) formation, a stra...

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Literature Corpus work
c2d48b55-a9a0-51c9-872f-448cb5761feb
DOI
10.1101/2023.07.10.548404
Open publication

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