Article
Rough and smooth variant <i>Mycobacterium abscessus</i> infections are differentially controlled by host immunity during chronic infection
2019-11-29
Abstract excerpt
Infections caused by Mycobacterium abscessus are increasing in prevalence within patient groups with respiratory comorbidities. Initial colonisation by the smooth colony M. abscessus (S) can be followed by an irreversible genetic switch into a highly inflammatory rough colony M. abscessus (R), often associated with a decline in pulmonary function. Our understanding of the role of adaptive immunity in M. absces...
Topics
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- Antifungal resistance and susceptibility
- Antimicrobial Peptides and Activities
- Aquaculture disease management and microbiota
- Bacteriophages and microbial interactions
- Cancer-related molecular mechanisms research
- Fungal Infections and Studies
- Mycobacterium research and diagnosis
- Tuberculosis Research and Epidemiology
Identifiers and source
- Literature Corpus work
- 310a9630-88a4-513b-a7bc-2de156a88703
- DOI
- 10.1101/856948
