Article

Glutamine addiction is a therapeutic target to block emergency myelopoiesis

2026-03-30

Abstract excerpt

Inflammation-driven emergency myelopoiesis (EM) contributes to the progression of many solid cancers and inflammatory diseases, yet therapeutic strategies to selectively suppress EM without compromising hematopoiesis remain lacking. Here, we use functional and single-cell transcriptomic analyses to determine metabolic programs organizing the hematopoietic hierarchy, myeloid lineage commitment, and myeloid differen...

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Literature Corpus work: e8ef0bf4-b992-5350-b445-4e17c0fb5fc1
DOI: 10.64898/2026.03.26.714544

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