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The Epithelial to Mesenchymal Transition Promotes Glutamine Independence by Suppressing GLS2 Expression

22 Oct 2019

Abstract excerpt

Identifying bioenergetics that facilitate the epithelial to mesenchymal transition (EMT) in breast cancer cells may uncover targets to treat incurable metastatic disease. Metastasis is the number one cause of cancer-related deaths; therefore, it is urgent to identify new treatment strategies to prevent the initiation of metastasis. To characterize the bioenergetics of EMT, we compared metabolic activities and...

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PMID: 31652551
DOI: 10.3390/cancers11101610

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