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Exploiting metabolic vulnerabilities for personalized therapy in acute myeloid leukemia

18 Jul 2019

Abstract excerpt

Changes in cell metabolism and metabolic adaptation are hallmark features of many cancers, including leukemia, that support biological processes involved into tumor initiation, growth, and response to therapeutics. The discovery of mutations in key metabolic enzymes has highlighted the importance of metabolism in cancer biology and how these changes might constitute an Achilles heel for cancer treatment. In this...

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PMID: 31319822
DOI: 10.1186/s12915-019-0670-4

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