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Single cell RNA sequencing to dissect the molecular heterogeneity in lupus nephritis

3 May 2017

Abstract excerpt

Lupus nephritis is a leading cause of mortality among systemic lupus erythematosus (SLE) patients, and its heterogeneous nature poses a significant challenge to the development of effective diagnostics and treatments. Single cell RNA sequencing (scRNA-seq) offers a potential solution to dissect the heterogeneity of the disease and enables the study of similar cell types distant from the site of renal injury to...

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PMID: 28469080
DOI: 10.1172/jci.insight.93009

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