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Essential conserved neuronal motors kinesin-1 and kinesin-3 regulate Aβ42 toxicity in vivo

2024-04-23

Abstract excerpt

Alzheimer’s Disease is the leading cause of dementia and the most common neurodegenerative disorder. Understanding the molecular pathology of Alzheimer’s Disease may help identify new ways to reduce neuronal damage. In the past decades Drosophila has become a powerful tool in modelling mechanisms underlying human diseases. Here we investigate how the expression of the human 42-residue β-amyloid (Aβ) carrying the...

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Literature Corpus work
e8b98a20-6e90-5b83-8e86-ff30a3ae25b3
DOI
10.1101/2024.04.23.590704
Open publication

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Essential conserved neuronal motors kinesin-1 and kinesin-3 regulate Aβ42 toxicity in vivoDOI 10.1101/2024.04.23.590704
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