Article

CRISPR interference in a <i>Streptococcus agalactiae</i> Multi-locus Sequence Type 17 Strain

2025-08-27

Abstract excerpt

Group B Streptococcus (GBS), a common colonizer of the human genital and gastrointestinal tracts, is a leading cause of neonatal bacterial meningitis, which can lead to severe neurological complications. The hypervirulent serotype III, sequence type 17 (ST-17) strain COH1 is strongly associated with late-onset disease due to its unique set of virulence factors. However, genetic manipulation of ST-17 strains is not...

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Literature Corpus work: e88ff80a-4f97-513f-b06b-de5085c2dea0
DOI: 10.1101/2025.08.27.672580

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