Article

RET activation controlled by MAB21L4-CacyBP interaction drives squamous cell carcinoma

2022-01-22

Abstract excerpt

Epithelial squamous cell carcinomas (SCC) most commonly originate in the skin, where they display disruptions in the normally tightly regulated homeostatic balance between keratinocyte proliferation and terminal differentiation. We performed a transcriptome-wide screen for genes of unknown function that possess inverse expression patterns in differentiating keratinocytes compared to cutaneous SCC (cSCC) and identi...

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Literature Corpus work: e861c05c-0db0-5a4b-a88e-7bffd1051644
DOI: 10.1101/2022.01.19.476979

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