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Article

FGFR2 signaling underlies p63 oncogenic function in squamous cell carcinoma

7 Jul 2013

Abstract excerpt

Oncogenic transcription factors drive many human cancers, yet identifying and therapeutically targeting the resulting deregulated pathways has proven difficult. Squamous cell carcinoma (SCC) is a common and lethal human cancer, and relatively little progress has been made in improving outcomes for SCC due to a poor understanding of its underlying molecular pathogenesis. While SCCs typically lack somatic...

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PMID: 23867503
DOI: 10.1172/jci68899

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