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Article

UVB induces cutaneous squamous cell carcinoma progression by de novo ID4 methylation via methylation regulating enzymes

20 Jun 2020

Abstract excerpt

BACKGROUND: Little is known about whether UVB can directly influence epigenetic regulatory pathways to induce cutaneous squamous cell carcinoma (CSCC). This study aimed to identify epigenetic-regulated signalling pathways through global methylation and gene expression profiling and to elucidate their function in CSCC development. METHODS: Global DNA methylation profiling by reduced representation bisulfite...

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PMID: 32574963
DOI: 10.1016/j.ebiom.2020.102835

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