Article

Phosphoproteomic analysis of the AKT signalling axis in cutaneous squamous carcinoma progression reveals novel therapeutic targets

2022-10-05

Abstract excerpt

Cutaneous Squamous Cell Carcinoma (cSCC) represents about 20% of all non-melanoma skin cancers. Whilst generally low risk to patients, metastases are associated with a poor prognosis. cSCC incidence is increasing, owing to an ageing population, greater exposure to UV radiation, and more patients receiving immunosuppressive treatments associated with organ transplants. Therefore, there is interest in identifying ne...

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Literature Corpus work: 0c8d04f6-7dc1-5c54-b2e8-6fcf8056fc82
DOI: 10.1101/2022.10.03.510591

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