Article

CamoTSS: analysis of alternative transcription start sites for cellular phenotypes and regulatory patterns from 5’ scRNA-seq data

2023-04-18

Abstract excerpt

Five-prime single-cell RNA-seq (scRNA-seq) has been widely employed to profile cellular transcriptomes, however, its power of analysing transcription start sites (TSS) has not been fully utilised. Here, we present a computational method suite, CamoTSS, to precisely identify TSS and quantify its expression by leveraging the cDNA on read 1, which enables effective detection of alternative TSS usage. With various exp...

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Literature Corpus work: 349b78b6-e556-57ba-aaa5-a71f69e18476
DOI: 10.1101/2023.04.17.536840

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