Article

A catalog of transcription start sites across 115 human tissue and cell types

2021-05-13

Abstract excerpt

Accurate transcription start site (TSS) annotations are essential for understanding transcriptional regulation and its role in human disease. Gene collections such as GENCODE contain annotations for tens of thousands of TSSs, but not all of these annotations are experimentally validated nor do they contain information on cell type-specific usage. Therefore, we sought to generate a collection of experimentally vali...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 2efc23c8-0952-5c81-a2c0-8a317844136f
DOI: 10.1101/2021.05.12.443890

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

A catalog of transcription start sites across 115 human tissue and cell typesDOI 10.1101/2021.05.12.443890Read

Flexible analysis of TSS mapping data and detection of TSS shifts with TSRexploreRSemantic proximity Read

The nascent transcriptome delineates the regulatory landscape in human health and diseaseSemantic proximity Read

A single-cell atlas of transcribed <i>cis</i> -regulatory elements in the human genomeSemantic proximity Read

Simple and efficient measurement of transcription initiation and transcript levels with STRIPE-seqSemantic proximity Read

Transcription initiation mapping in 31 bovine tissues reveals complex promoter activity, pervasive transcription, and tissue-specific promoter usageSemantic proximity Read

Profiling of transcribed <i>cis</i> -regulatory elements in single cellsSemantic proximity Read

A transcription start site map in human pancreatic islets reveals functional regulatory signaturesSemantic proximity Read

A Transcription Start Site Map in Human Pancreatic Islets Reveals Functional Regulatory Signatures.Semantic proximity Read

Integrative nascent RNA methods to reveal cell-type specific transcription programs in peripheral blood and its derivative cellsSemantic proximity Read

Integrative nascent RNA methods to reveal cell-type specific transcription programs in peripheral blood and its derivative cellsSemantic proximity Read

STARRPeaker: Uniform processing and accurate identification of STARR-seq active regionsSemantic proximity Read

ReCappable Seq: Comprehensive Determination of Transcription Start Sites derived from all RNA polymerasesSemantic proximity Read