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Article

Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal Fluid

2021-05-16

Abstract excerpt

<h4>Importance</h4> Malignant neoplasms of the central nervous system (CNS) are frequently not detected by cerebrospinal fluid (CSF) flow cytometry or cytology, and clinical phenotypes can overlap with inflammatory meningoencephalitis. <h4>Objective</h4> To determine whether an existing CSF metagenomic next-generation sequencing (mNGS) assay can identify a hallmark of malignant neoplasms — aneuploidy — in difficul...

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Literature Corpus work
e79b4f45-64f8-5895-94b2-f9a7ce52c7d4
DOI
10.1101/2021.05.13.21256918
Open publication

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Detection of Neoplasms by Metagenomic Sequencing of Cerebrospinal FluidDOI 10.1101/2021.05.13.21256918
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